William Frederick Fisher
- Status: Retired
- In Space: No
- Date of Birth: 04/01/1946
- First Flight: 08/27/1985
- Last Flight: 08/27/1985
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William Frederick Fisher, a American astronaut affiliated with the government agency National Aeronautics and Space Administration, embarked on 1 space flights and engaging in 2 spacewalks during his/her career as an astronaut.
William Frederick Fisher is an American physician and a former NASA astronaut. Fisher went into space in 1985 on board the Space Shuttle. He retired from NASA in 1992 and returned to the full-time practice of medicine. His time at NASA coincided with that of his former wife and fellow astronaut Anna Lee Fisher.